Huntington’s disease, a genetic disorder that causes the progressive breakdown of nerve cells in the brain, was poorly understood when Nancy Wexler first began studying the disease as a young scientist. In an exclusive, multipart interview with the Lasker Foundation, Wexler discusses her life’s work to increase awareness and find therapies for Huntington’s disease.

Chapter 1: Personal reflections on Huntington’s disease

Chapter 2: Mapping and cloning the Huntington’s gene

Chapter 3: Looking for therapies

Chapter 4: Do gene variants protect?

Chapter 5: Ethical, legal and social implications of genetic research

Chapter 6: Winning the Lasker Award

Chapter 7: Are you optimistic about the future of Huntington’s research?