In this opinion piece for Fox News, Lasker President Claire Pomeroy argues that the threat posed from bacteria that have evolved resistance to the most powerful strains of antibiotics must be taken seriously. To stem the threat, investigators must embrace the importance of researching new and effective antibiotics; policymakers must ensure that regulations do not discourage R&D; and pharmaceutical companies must invest in their development. And the public must raise its voice to support funding research into the next generation of drugs to combat evolving infectious disease.