The Keck School of Medicine of USC is the first medical school in the nation to host the Lasker Lectures, featuring recipients of the prestigious 2013 Albert Lasker Basic Medical Research Award. In this installment, Thomas Südhof, Professor of Molecular and Cellular Physiology at Stanford University School of Medicine, recipient of the 2013 Nobel Prize in Physiology or Medicine, discusses the mechanism of neurotransmitter release.