cGAS enzyme that senses self and foreign DNAZhijian “James” ChenLasker Admin2024-10-07T09:06:56-04:00Year of awards: 2024| Awards: BASIC|
AlphaFold—for predicting protein structuresDemis Hassabis, John JumperLasker Admin2024-08-14T14:25:09-04:00Year of awards: 2023| Awards: BASIC|
Integrins—mediators of cell-matrix and cell-cell adhesionRichard O. Hynes, Erkki Ruoslahti, Timothy A. SpringerLasker Admin2023-09-13T14:14:08-04:00Year of awards: 2022| Awards: BASIC|
Light-sensitive microbial proteins and optogeneticsKarl Deisseroth, Peter Hegemann, Dieter OesterheltLasker Admin2022-01-27T17:12:17-05:00Year of awards: 2021| Awards: BASIC|
B and T cells—the organizing principle of the adaptive immune systemMax D. Cooper, Jacques MillerLasker Admin2021-04-29T14:49:09-04:00Year of awards: 2019| Awards: BASIC|
Histone modifications and gene expressionC. David Allis, Michael GrunsteinLasker Admin2021-02-27T15:23:29-05:00Year of awards: 2018| Awards: BASIC|
Nutrient-activated TOR proteins that regulate cell growthMichael N. HallLasker Admin2021-02-27T15:27:24-05:00Year of awards: 2017| Awards: BASIC|
Oxygen sensing – an essential process for survivalWilliam G. Kaelin, Jr., Peter J. Ratcliffe, Gregg L. SemenzaLasker Admin2021-05-27T15:40:33-04:00Year of awards: 2016| Awards: BASIC|
Discoveries concerning the DNA-damage responseStephen J. Elledge, Evelyn M. WitkinLasker Admin2021-02-27T15:33:01-05:00Year of awards: 2015| Awards: BASIC|
Unfolded protein responseKazutoshi Mori, Peter WalterLasker Admin2021-02-27T15:35:15-05:00Year of awards: 2014| Awards: BASIC|
Regulated neurotransmitter releaseRichard H. Scheller, Thomas C. SüdhofLasker Admin2021-02-27T15:37:34-05:00Year of awards: 2013| Awards: BASIC|
Motor proteins that contract muscles and enable cell movementsMichael Sheetz, James Spudich, Ronald ValeLasker Admin2021-02-27T15:40:12-05:00Year of awards: 2012| Awards: BASIC|
Chaperone-assisted protein foldingFranz-Ulrich Hartl, Arthur L. HorwichLasker Admin2021-02-27T15:42:47-05:00Year of awards: 2011| Awards: BASIC|
Leptin, a hormone that regulates appetite and body weightDouglas Coleman, Jeffrey M. FriedmanLasker Admin2021-02-27T15:45:47-05:00Year of awards: 2010| Awards: BASIC|
Nuclear reprogramming: converting specialized cells into early stem cellsJohn Gurdon, Shinya YamanakaLasker Admin2021-02-27T15:47:34-05:00Year of awards: 2009| Awards: BASIC|
Tiny RNAs that regulate gene functionVictor R. Ambros, David C. Baulcombe, Gary B. RuvkunLasker Admin2021-02-27T15:49:12-05:00Year of awards: 2008| Awards: BASIC|
